NGS-based identification and tracing of microsatellite instability from minute amounts DNA using inter-Alu-PCR

Sensitive detection of microsatellite instability (MSI) in tissue or liquid biopsies using next generation sequencing (NGS) has growing prognostic and predictive applications in cancer. However, the complexities of NGS make it cumbersome as compared to established multiplex-PCR detection of MSI. We...

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Detalles Bibliográficos
Autores principales: Yu, Fangyan, Leong, Ka Wai, Makrigiorgos, Alexander, Adalsteinsson, Viktor A, Ladas, Ioannis, Ng, Kimmie, Mamon, Harvey, Makrigiorgos, G Mike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913684/
https://www.ncbi.nlm.nih.gov/pubmed/33290560
http://dx.doi.org/10.1093/nar/gkaa1175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913684/
https://www.ncbi.nlm.nih.gov/pubmed/33290560
http://dx.doi.org/10.1093/nar/gkaa1175

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