In vitro selected GUAA tetraloop-binding receptors with structural plasticity and evolvability towards natural RNA structural modules

GNRA tetraloop-binding receptor interactions are key components in the macromolecular assembly of a variety of functional RNAs. In nature, there is an apparent bias for GAAA/11nt receptor and GYRA/helix interactions, with the former interaction being thermodynamically more stable than the latter. Wh...

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Detalles Bibliográficos
Autores principales: Zakrevsky, Paul, Calkins, Erin, Kao, Yi-Ling, Singh, Gurkeerat, Keleshian, Vasken L, Baudrey, Stephanie, Jaeger, Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913685/
https://www.ncbi.nlm.nih.gov/pubmed/33524109
http://dx.doi.org/10.1093/nar/gkab021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913685/
https://www.ncbi.nlm.nih.gov/pubmed/33524109
http://dx.doi.org/10.1093/nar/gkab021

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