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Dinucleotides as simple models of the base stacking-unstacking component of DNA ‘breathing’ mechanisms
Regulatory protein access to the DNA duplex ‘interior’ depends on local DNA ‘breathing’ fluctuations, and the most fundamental of these are thermally-driven base stacking-unstacking interactions. The smallest DNA unit that can undergo such transitions is the dinucleotide, whose structural and dynami...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913701/ https://www.ncbi.nlm.nih.gov/pubmed/33503257 http://dx.doi.org/10.1093/nar/gkab015 |