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Deuterium Oxide (D(2)O) Induces Early Stress Response Gene Expression and Impairs Growth and Metastasis of Experimental Malignant Melanoma

SIMPLE SUMMARY: Systemic administration of deuterium oxide (‘heavy water’) has shown promise in suppressing tumor growth and metastasis in mammalian cancer models, but no detailed molecular studies have revealed specific molecular pathways mediating cancer-cell-directed activities. Here, for the fir...

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Detalles Bibliográficos
Autores principales: Jandova, Jana, Hua, Anh B., Fimbres, Jocelyn, Wondrak, Georg T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913703/
https://www.ncbi.nlm.nih.gov/pubmed/33546433
http://dx.doi.org/10.3390/cancers13040605