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Dangerous Stops: Nonsense Mutations Can Dramatically Increase Frequency of Prion Conversion

Amyloid formation is associated with many incurable diseases. For some of these, sporadic cases are much more common than familial ones. Some reports point to the role of somatic cell mosaicism in these cases via origination of amyloids in a limited number of cells, which can then spread through tis...

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Detalles Bibliográficos
Autores principales: Dergalev, Alexander A., Urakov, Valery N., Agaphonov, Michael O., Alexandrov, Alexander I., Kushnirov, Vitaly V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913716/
https://www.ncbi.nlm.nih.gov/pubmed/33546497
http://dx.doi.org/10.3390/ijms22041542