Optimized Detoxification of a Live Attenuated Vaccine Strain (SG9R) to Improve Vaccine Strategy against Fowl Typhoid

The live attenuated vaccine strain, SG9R, has been used against fowl typhoid worldwide, but it can revert to the pathogenic smooth strain owing to single nucleotide changes such as nonsense mutations in the rfaJ gene. As SG9R possesses an intact Salmonella plasmid with virulence genes, it exhibits d...

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Detalles Bibliográficos
Autores principales: Kim, Nam-Hyung, Ko, Dae-Sung, Ha, Eun-Jin, Ahn, Sunmin, Choi, Kang-Seuk, Kwon, Hyuk-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913755/
https://www.ncbi.nlm.nih.gov/pubmed/33546449
http://dx.doi.org/10.3390/vaccines9020122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913755/
https://www.ncbi.nlm.nih.gov/pubmed/33546449
http://dx.doi.org/10.3390/vaccines9020122

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