Lamin B1 acetylation slows the G1 to S cell cycle transition through inhibition of DNA repair

The integrity and regulation of the nuclear lamina is essential for nuclear organization and chromatin stability, with its dysregulation being linked to laminopathy diseases and cancer. Although numerous posttranslational modifications have been identified on lamins, few have been ascribed a regulat...

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Detalles Bibliográficos
Autores principales: Murray-Nerger, Laura A, Justice, Joshua L, Rekapalli, Pranav, Hutton, Josiah E, Cristea, Ileana M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913768/
https://www.ncbi.nlm.nih.gov/pubmed/33533922
http://dx.doi.org/10.1093/nar/gkab019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913768/
https://www.ncbi.nlm.nih.gov/pubmed/33533922
http://dx.doi.org/10.1093/nar/gkab019

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