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Lamin B1 acetylation slows the G1 to S cell cycle transition through inhibition of DNA repair
The integrity and regulation of the nuclear lamina is essential for nuclear organization and chromatin stability, with its dysregulation being linked to laminopathy diseases and cancer. Although numerous posttranslational modifications have been identified on lamins, few have been ascribed a regulat...
Autores principales: | Murray-Nerger, Laura A, Justice, Joshua L, Rekapalli, Pranav, Hutton, Josiah E, Cristea, Ileana M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913768/ https://www.ncbi.nlm.nih.gov/pubmed/33533922 http://dx.doi.org/10.1093/nar/gkab019 |
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