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Structural basis of diversity and homodimerization specificity of zinc-finger-associated domains in Drosophila

In arthropods, zinc finger-associated domains (ZADs) are found at the N-termini of many DNA-binding proteins with tandem arrays of Cys2-His2 zinc fingers (ZAD-C2H2 proteins). ZAD-C2H2 proteins undergo fast evolutionary lineage-specific expansion and functional diversification. Here, we show that all...

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Detalles Bibliográficos
Autores principales: Bonchuk, Artem, Boyko, Konstantin, Fedotova, Anna, Nikolaeva, Alena, Lushchekina, Sofya, Khrustaleva, Anastasia, Popov, Vladimir, Georgiev, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913770/
https://www.ncbi.nlm.nih.gov/pubmed/33638995
http://dx.doi.org/10.1093/nar/gkab061