Alignment free identification of clones in B cell receptor repertoires

Following antigenic challenge, activated B cells rapidly expand and undergo somatic hypermutation, yielding groups of clonally related B cells with diversified immunoglobulin receptors. Inference of clonal relationships based on the receptor sequence is an essential step in many adaptive immune rece...

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Detalles Bibliográficos
Autores principales: Lindenbaum, Ofir, Nouri, Nima, Kluger, Yuval, Kleinstein, Steven H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913774/
https://www.ncbi.nlm.nih.gov/pubmed/33330933
http://dx.doi.org/10.1093/nar/gkaa1160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913774/
https://www.ncbi.nlm.nih.gov/pubmed/33330933
http://dx.doi.org/10.1093/nar/gkaa1160

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