Development and Characterization of Sustained-Released Donepezil Hydrochloride Solid Dispersions Using Hot Melt Extrusion Technology

The aim of this work was to develop the sustained release formulation of donepezil hydrochloride (DH) using the hot-melt extruded solid dispersion technique via the rational screening of hydrophobic carriers. Hydrophobic carriers with different physicochemical properties such as pH-independent swell...

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Detalles Bibliográficos
Autores principales: Alshetaili, Abdullah, Almutairy, Bjad K., Alshehri, Sultan M., Repka, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913813/
https://www.ncbi.nlm.nih.gov/pubmed/33557076
http://dx.doi.org/10.3390/pharmaceutics13020213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913813/
https://www.ncbi.nlm.nih.gov/pubmed/33557076
http://dx.doi.org/10.3390/pharmaceutics13020213

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