Molecular Mechanisms of Senescence and Implications for the Treatment of Myeloid Malignancies

SIMPLE SUMMARY: Senescence is a cellular program in response to stress and can prevent the expansion of pre-malignant and malignant cells by cell cycle arrest. However, long-term pro-tumorigenic effects have been described. This review aims to compile molecular mechanisms of cellular senescence and...

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Detalles Bibliográficos
Autores principales: Ernst, Philipp, Heidel, Florian H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913823/
https://www.ncbi.nlm.nih.gov/pubmed/33557090
http://dx.doi.org/10.3390/cancers13040612

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913823/
https://www.ncbi.nlm.nih.gov/pubmed/33557090
http://dx.doi.org/10.3390/cancers13040612

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