A Transcription Regulatory Sequence in the 5′ Untranslated Region of SARS-CoV-2 Is Vital for Virus Replication with an Altered Evolutionary Pattern against Human Inhibitory MicroRNAs

Our knowledge of the evolution and the role of untranslated region (UTR) in SARS-CoV-2 pathogenicity is very limited. Leader sequence, originated from UTR, is found at the 5′ ends of all encoded SARS-CoV-2 transcripts, highlighting its importance. Here, evolution of leader sequence was compared betw...

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Detalles Bibliográficos
Autores principales: Mohammadi-Dehcheshmeh, Manijeh, Moghbeli, Sadrollah Molaei, Rahimirad, Samira, Alanazi, Ibrahim O., Shehri, Zafer Saad Al, Ebrahimie, Esmaeil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913991/
https://www.ncbi.nlm.nih.gov/pubmed/33557205
http://dx.doi.org/10.3390/cells10020319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913991/
https://www.ncbi.nlm.nih.gov/pubmed/33557205
http://dx.doi.org/10.3390/cells10020319

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