A Multivariate Approach for the Determination of the Optimal Mixing Ratio of the Non-Strong Interacting Co-Amorphous System Carvedilol-Tryptophan

Converting crystalline compounds into co-amorphous systems is an effective way to improve the solubility of poorly water-soluble drugs. It is, however, of critical importance for the physical stability of co-amorphous systems to find the optimal mixing ratio of the drug with the co-former. In this s...

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Detalles Bibliográficos
Autores principales: Di, Rong, Liu, Jingwen, Grohganz, Holger, Rades, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913994/
https://www.ncbi.nlm.nih.gov/pubmed/33557164
http://dx.doi.org/10.3390/molecules26040801

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913994/
https://www.ncbi.nlm.nih.gov/pubmed/33557164
http://dx.doi.org/10.3390/molecules26040801

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