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Novel Pannexin-1-Coupled Signaling Cascade Involved in the Control of Endothelial Cell Function and NO-Dependent Relaxation

Deletion of pannexin-1 (Panx-1) leads not only to a reduction in endothelium-derived hyperpolarization but also to an increase in NO-mediated vasodilation. Therefore, we evaluated the participation of Panx-1-formed channels in the control of membrane potential and [Ca(2+)](i) of endothelial cells. C...

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Detalles Bibliográficos
Autores principales: Lillo, Mauricio A., Gaete, Pablo S., Puebla, Mariela, Burboa, Pía C., Poblete, Inés, Figueroa, Xavier F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914086/
https://www.ncbi.nlm.nih.gov/pubmed/33688389
http://dx.doi.org/10.1155/2021/2678134