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Novel Pannexin-1-Coupled Signaling Cascade Involved in the Control of Endothelial Cell Function and NO-Dependent Relaxation
Deletion of pannexin-1 (Panx-1) leads not only to a reduction in endothelium-derived hyperpolarization but also to an increase in NO-mediated vasodilation. Therefore, we evaluated the participation of Panx-1-formed channels in the control of membrane potential and [Ca(2+)](i) of endothelial cells. C...
Autores principales: | Lillo, Mauricio A., Gaete, Pablo S., Puebla, Mariela, Burboa, Pía C., Poblete, Inés, Figueroa, Xavier F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914086/ https://www.ncbi.nlm.nih.gov/pubmed/33688389 http://dx.doi.org/10.1155/2021/2678134 |
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