Structural basis for placental malaria mediated by Plasmodium falciparum VAR2CSA

Plasmodium falciparum VAR2CSA binds to chondroitin sulfate A (CSA) on the surface of the syncytiotrophoblast during placental malaria. This interaction facilitates placental sequestration of malaria parasites resulting in severe health outcomes for both the mother and her offspring. Furthermore, CSA...

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Detalles Bibliográficos
Autores principales: Ma, Rui, Lian, Tengfei, Huang, Rick, Renn, Jonathan P., Petersen, Jennifer D., Zimmerberg, Joshua, Duffy, Patrick E., Tolia, Niraj H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914210/
https://www.ncbi.nlm.nih.gov/pubmed/33452495
http://dx.doi.org/10.1038/s41564-020-00858-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914210/
https://www.ncbi.nlm.nih.gov/pubmed/33452495
http://dx.doi.org/10.1038/s41564-020-00858-9

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