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Serotonin-specific neurons differentiated from human iPSCs form distinct subtypes with synaptic protein assembly

Human induced pluripotent stem cells (hiPSCs) have revolutionized the generation of experimental disease models, but the development of protocols for the differentiation of functionally active neuronal subtypes with defined specification is still in its infancy. While dysfunction of the brain seroto...

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Detalles Bibliográficos
Autores principales: Jansch, Charline, Ziegler, Georg C., Forero, Andrea, Gredy, Sina, Wäldchen, Sina, Vitale, Maria Rosaria, Svirin, Evgeniy, Zöller, Johanna E. M., Waider, Jonas, Günther, Katharina, Edenhofer, Frank, Sauer, Markus, Wischmeyer, Erhard, Lesch, Klaus-Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914246/
https://www.ncbi.nlm.nih.gov/pubmed/33560471
http://dx.doi.org/10.1007/s00702-021-02303-5