TRIM41 is required to innate antiviral response by polyubiquitinating BCL10 and recruiting NEMO

Sensing of pathogenic nucleic acids by pattern recognition receptors (PRR) not only initiates anti-microbe defense but causes inflammatory and autoimmune diseases. E3 ubiquitin ligase(s) critical in innate response need to be further identified. Here we report that the tripartite motif-containing E3...

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Detalles Bibliográficos
Autores principales: Yu, Zhou, Li, Xuelian, Yang, Mingjin, Huang, Jiaying, Fang, Qian, Jia, Jianjun, Li, Zheng, Gu, Yan, Chen, Taoyong, Cao, Xuetao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914255/
https://www.ncbi.nlm.nih.gov/pubmed/33640899
http://dx.doi.org/10.1038/s41392-021-00477-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914255/
https://www.ncbi.nlm.nih.gov/pubmed/33640899
http://dx.doi.org/10.1038/s41392-021-00477-8

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