Granzyme A inhibition reduces inflammation and increases survival during abdominal sepsis

Aims: Peritonitis is one of the most common causes of sepsis, a serious syndrome characterized by a dysregulated systemic inflammatory response. Recent evidence suggests that Granzyme A (GzmA), a serine protease mainly expressed by NK and T cells, could act as a proinflammatory mediator and could pl...

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Detalles Bibliográficos
Autores principales: Garzón-Tituaña, Marcela, Sierra-Monzón, José L, Comas, Laura, Santiago, Llipsy, Khaliulina-Ushakova, Tatiana, Uranga-Murillo, Iratxe, Ramirez-Labrada, Ariel, Tapia, Elena, Morte-Romea, Elena, Algarate, Sonia, Couty, Ludovic, Camerer, Eric, Bird, Phillip I, Seral, Cristina, Luque, Pilar, Paño-Pardo, José R, Galvez, Eva M, Pardo, Julián, Arias, Maykel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914344/
https://www.ncbi.nlm.nih.gov/pubmed/33664861
http://dx.doi.org/10.7150/thno.49288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914344/
https://www.ncbi.nlm.nih.gov/pubmed/33664861
http://dx.doi.org/10.7150/thno.49288

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