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PRMT5 functionally associates with EZH2 to promote colorectal cancer progression through epigenetically repressing CDKN2B expression

Background: Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that symmetrically di-methylates arginine residues on both histone and non-histone protein substrates. Accumulating evidence suggests that PRMT5 exerts its oncogenic properties in a wide spectrum of huma...

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Detalles Bibliográficos
Autores principales: Yang, Liu, Ma, Da-wei, Cao, Yue-peng, Li, Dong-zheng, Zhou, Xin, Feng, Ji-feng, Bao, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914347/
https://www.ncbi.nlm.nih.gov/pubmed/33664859
http://dx.doi.org/10.7150/thno.53023