Downregulation of death receptor 4 is tightly associated with positive response of EGFR mutant lung cancer to EGFR-targeted therapy and improved prognosis

Death receptor 4 (DR4), a cell surface receptor, mediates apoptosis or induces inflammatory cytokine secretion upon binding to its ligand depending on cell contexts. Its prognostic impact in lung cancer and connection between EGFR-targeted therapy and DR4 modulation has not been reported and thus wa...

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Detalles Bibliográficos
Autores principales: Zhang, Shuo, Chen, Zhen, Shi, Puyu, Fan, Songqing, He, Yong, Wang, Qiming, Li, Yixiang, Ramalingam, Suresh S., Owonikoko, Taofeek K., Sun, Shi-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914351/
https://www.ncbi.nlm.nih.gov/pubmed/33664875
http://dx.doi.org/10.7150/thno.54824

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914351/
https://www.ncbi.nlm.nih.gov/pubmed/33664875
http://dx.doi.org/10.7150/thno.54824

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