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KDM6B-mediated histone demethylation of LDHA promotes lung metastasis of osteosarcoma

Rationale: Osteosarcoma (OS), the most common type of bone tumor, which seriously affects the patients' limb function and life quality. OS has a strong tendency of lung metastasis, and the five-year survival rate of patients with metastatic osteosarcoma is less than 20%. Thus, new treatment tar...

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Detalles Bibliográficos
Autores principales: Jiang, Yuhang, Li, Fengfeng, Gao, Bowen, Ma, Mengjun, Chen, Meng, Wu, Yanfeng, Zhang, Weidong, Sun, Yangbai, Liu, Sanhong, Shen, Huiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914357/
https://www.ncbi.nlm.nih.gov/pubmed/33664867
http://dx.doi.org/10.7150/thno.53347