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Diethylstilbestrol Modifies the Structure of Model Membranes and Is Localized Close to the First Carbons of the Fatty Acyl Chains

The synthetic estrogen diethylstilbestrol (DES) is used to treat metastatic carcinomas and prostate cancer. We studied its interaction with membranes and its localization to understand its mechanism of action and side-effects. We used differential scanning calorimetry (DSC) showing that DES fluidize...

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Detalles Bibliográficos
Autores principales: Ausili, Alessio, Rodríguez-González, Inés, Torrecillas, Alejandro, Teruel, José A., Gómez-Fernández, Juan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914449/
https://www.ncbi.nlm.nih.gov/pubmed/33557377
http://dx.doi.org/10.3390/biom11020220