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Cells Lacking PA200 Adapt to Mitochondrial Dysfunction by Enhancing Glycolysis via Distinct Opa1 Processing

The conserved Blm10/PA200 proteins are proteasome activators. Previously, we identified PA200-enriched regions in the genome of SH-SY5Y neuroblastoma cells by chromatin immunoprecipitation (ChIP) and ChIP-seq analysis. We also found that selective mitochondrial inhibitors induced PA200 redistributio...

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Detalles Bibliográficos
Autores principales: Douida, Abdennour, Batista, Frank, Boto, Pal, Regdon, Zsolt, Robaszkiewicz, Agnieszka, Tar, Krisztina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914502/
https://www.ncbi.nlm.nih.gov/pubmed/33562813
http://dx.doi.org/10.3390/ijms22041629