Initial Identification of UDP-Glucose Dehydrogenase as a Prognostic Marker in Breast Cancer Patients, Which Facilitates Epirubicin Resistance and Regulates Hyaluronan Synthesis in MDA-MB-231 Cells

UDP-glucose-dehydrogenase (UGDH) synthesizes UDP-glucuronic acid. It is involved in epirubicin detoxification and hyaluronan synthesis. This work aimed to evaluate the effect of UGDH knockdown on epirubicin response and hyaluronan metabolism in MDA-MB-231 breast cancer cells. Additionally, the aim w...

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Detalles Bibliográficos
Autores principales: Vitale, Daiana L., Caon, Ilaria, Parnigoni, Arianna, Sevic, Ina, Spinelli, Fiorella M., Icardi, Antonella, Passi, Alberto, Vigetti, Davide, Alaniz, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914570/
https://www.ncbi.nlm.nih.gov/pubmed/33572239
http://dx.doi.org/10.3390/biom11020246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914570/
https://www.ncbi.nlm.nih.gov/pubmed/33572239
http://dx.doi.org/10.3390/biom11020246

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