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Efficient Ocular Delivery of VCP siRNA via Reverse Magnetofection in RHO P23H Rodent Retina Explants

The use of synthetic RNA for research purposes as well as RNA-based therapy and vaccination has gained increasing importance. Given the anatomical seclusion of the eye, small interfering RNA (siRNA)-induced gene silencing bears great potential for targeted reduction of pathological gene expression t...

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Detalles Bibliográficos
Autores principales: Sen, Merve, Bassetto, Marco, Poulhes, Florent, Zelphati, Olivier, Ueffing, Marius, Arango-Gonzalez, Blanca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914601/
https://www.ncbi.nlm.nih.gov/pubmed/33562020
http://dx.doi.org/10.3390/pharmaceutics13020225