Cargando…
Efficient Ocular Delivery of VCP siRNA via Reverse Magnetofection in RHO P23H Rodent Retina Explants
The use of synthetic RNA for research purposes as well as RNA-based therapy and vaccination has gained increasing importance. Given the anatomical seclusion of the eye, small interfering RNA (siRNA)-induced gene silencing bears great potential for targeted reduction of pathological gene expression t...
Autores principales: | Sen, Merve, Bassetto, Marco, Poulhes, Florent, Zelphati, Olivier, Ueffing, Marius, Arango-Gonzalez, Blanca |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914601/ https://www.ncbi.nlm.nih.gov/pubmed/33562020 http://dx.doi.org/10.3390/pharmaceutics13020225 |
Ejemplares similares
-
Pharmacological Inhibition of the VCP/Proteasome Axis Rescues Photoreceptor Degeneration in RHO(P23H) Rat Retinal Explants
por: Sen, Merve, et al.
Publicado: (2021) -
Magnetically enhanced nucleic acid delivery. Ten years of magnetofection—Progress and prospects()
por: Plank, Christian, et al.
Publicado: (2011) -
Characterization, Stability, and In Vivo Efficacy Studies of Recombinant Human CNTF and Its Permeation into the Neural Retina in Ex Vivo Organotypic Retinal Explant Culture Models
por: Itkonen, Jaakko, et al.
Publicado: (2020) -
Combining Inulin Multifunctional Polycation and Magnetic Nanoparticles: Redox-Responsive siRNA-Loaded Systems for Magnetofection
por: Sardo, Carla, et al.
Publicado: (2019) -
Magnetically Assisted Drug Delivery of Topical Eye Drops Maintains Retinal Function In Vivo in Mice
por: Bassetto, Marco, et al.
Publicado: (2021)