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Understanding How Genetic Mutations Collaborate with Genomic Instability in Cancer

Chromosomal instability is the process of mis-segregation for ongoing chromosomes, which leads to cells with an abnormal number of chromosomes, also known as an aneuploid state. Induced aneuploidy is detrimental during development and in primary cells but aneuploidy is also a hallmark of cancer cell...

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Detalles Bibliográficos
Autores principales: Jilderda, Laura J., Zhou, Lin, Foijer, Floris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914657/
https://www.ncbi.nlm.nih.gov/pubmed/33562057
http://dx.doi.org/10.3390/cells10020342