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Inhibition of Mitochondrial Dynamics Preferentially Targets Pancreatic Cancer Cells with Enhanced Tumorigenic and Invasive Potential

SIMPLE SUMMARY: Due to their intrinsic aggressiveness, cancer stem cells (CSCs) represent an essential target for the design of effective treatments against pancreatic cancer, one of the deadliest tumors. As pancreatic CSCs are particularly dependent on the activity of their mitochondria, we here fo...

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Detalles Bibliográficos
Autores principales: Courtois, Sarah, de Luxán-Delgado, Beatriz, Penin-Peyta, Laure, Royo-García, Alba, Parejo-Alonso, Beatriz, Jagust, Petra, Alcalá, Sonia, Rubiolo, Juan A., Sánchez, Laura, Sainz, Bruno, Heeschen, Christopher, Sancho, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914708/
https://www.ncbi.nlm.nih.gov/pubmed/33572276
http://dx.doi.org/10.3390/cancers13040698