pH-Dependent Protein Binding Properties of Uremic Toxins In Vitro

Protein-bound uremic toxins (PBUTs) are difficult to remove using conventional dialysis treatment owing to their high protein-binding affinity. As pH changes the conformation of proteins, it may be associated with the binding of uremic toxins. Albumin conformation at pH 2 to 13 was analyzed using ci...

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Detalles Bibliográficos
Autores principales: Yamamoto, Suguru, Sasahara, Kenichi, Domon, Mio, Yamaguchi, Keiichi, Ito, Toru, Goto, Shin, Goto, Yuji, Narita, Ichiei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914709/
https://www.ncbi.nlm.nih.gov/pubmed/33557434
http://dx.doi.org/10.3390/toxins13020116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914709/
https://www.ncbi.nlm.nih.gov/pubmed/33557434
http://dx.doi.org/10.3390/toxins13020116

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