Interference with TGFβ1-Mediated Inflammation and Fibrosis Underlies Reno-Protective Effects of the CB1 Receptor Neutral Antagonists AM6545 and AM4113 in a Rat Model of Metabolic Syndrome

The role of cannabinoid receptors in nephropathy is gaining much attention. This study investigated the effects of two neutral CB1 receptor antagonists, AM6545 and AM4113, on nephropathy associated with metabolic syndrome (MetS). MetS was induced in rats by high-fructose high-salt feeding for 12 wee...

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Detalles Bibliográficos
Autores principales: Eid, Basma G., Neamatallah, Thikryat, Hanafy, Abeer, El-Bassossy, Hany M., Binmahfouz, Lenah, Aldawsari, Hibah M., Hasan, Atif, El-Aziz, Gamal Abd, Vemuri, Kiran, Makriyannis, Alexandros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914730/
https://www.ncbi.nlm.nih.gov/pubmed/33562080
http://dx.doi.org/10.3390/molecules26040866

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914730/
https://www.ncbi.nlm.nih.gov/pubmed/33562080
http://dx.doi.org/10.3390/molecules26040866

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