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Mutational Landscape of Virus- and UV-Associated Merkel Cell Carcinoma Cell Lines Is Comparable to Tumor Tissue

SIMPLE SUMMARY: Merkel cell carcinoma (MCC) is an aggressive, rare skin cancer which is caused either by a virus or chronic UV exposure. For both forms, distinct genetic alterations have been described; however, these observations were mostly made in tumor tissue. Since cancer cell lines are frequen...

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Detalles Bibliográficos
Autores principales: Horny, Kai, Gerhardt, Patricia, Hebel-Cherouny, Angela, Wülbeck, Corinna, Utikal, Jochen, Becker, Jürgen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914758/
https://www.ncbi.nlm.nih.gov/pubmed/33562873
http://dx.doi.org/10.3390/cancers13040649