Small Pore-Forming Toxins Different Membrane Area Binding and Ca(2+) Permeability of Pores Determine Cellular Resistance of Monocytic Cells †

Pore-forming toxins (PFTs) form multimeric trans-membrane pores in cell membranes that differ in pore channel diameter (PCD). Cellular resistance to large PFTs (>20 nm PCD) was shown to rely on Ca(2+) influx activated membrane repair mechanisms. Small PFTs (<2 nm PCD) were shown to exhibit a h...

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Detalles Bibliográficos
Autores principales: Larpin, Yu, Besançon, Hervé, Babiychuk, Victoriia S., Babiychuk, Eduard B., Köffel, René
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914786/
https://www.ncbi.nlm.nih.gov/pubmed/33572185
http://dx.doi.org/10.3390/toxins13020126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914786/
https://www.ncbi.nlm.nih.gov/pubmed/33572185
http://dx.doi.org/10.3390/toxins13020126

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