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Small Pore-Forming Toxins Different Membrane Area Binding and Ca(2+) Permeability of Pores Determine Cellular Resistance of Monocytic Cells †
Pore-forming toxins (PFTs) form multimeric trans-membrane pores in cell membranes that differ in pore channel diameter (PCD). Cellular resistance to large PFTs (>20 nm PCD) was shown to rely on Ca(2+) influx activated membrane repair mechanisms. Small PFTs (<2 nm PCD) were shown to exhibit a h...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914786/ https://www.ncbi.nlm.nih.gov/pubmed/33572185 http://dx.doi.org/10.3390/toxins13020126 |