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A Human Cellular Model for Colorectal Anastomotic Repair: The Effect of Localization and Transforming Growth Factor-β1 Treatment on Collagen Deposition and Biomarkers

Anastomotic leakage (AL) is a devastating complication after colorectal surgery, possibly due to the loss of stabilizing collagen fibers in the submucosa. Our aim was to assess the formation of collagen in the colon versus the rectum with or without transforming growth factor (TGF)-β1 exposure in a...

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Detalles Bibliográficos
Autores principales: Türlü, Ceylan, Willumsen, Nicholas, Marando, Debora, Schjerling, Peter, Biskup, Edyta, Hannibal, Jens, Jorgensen, Lars N., Ågren, Magnus S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914853/
https://www.ncbi.nlm.nih.gov/pubmed/33562728
http://dx.doi.org/10.3390/ijms22041616