Suppression of Hypoxia-Inducible Factor 1α by Low-Molecular-Weight Heparin Mitigates Ventilation-Induced Diaphragm Dysfunction in a Murine Endotoxemia Model

Mechanical ventilation (MV) is required to maintain life for patients with sepsis-related acute lung injury but can cause diaphragmatic myotrauma with muscle damage and weakness, known as ventilator-induced diaphragm dysfunction (VIDD). Hypoxia-inducible factor 1α (HIF-1α) plays a crucial role in in...

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Detalles Bibliográficos
Autores principales: Li, Li-Fu, Yu, Chung-Chieh, Huang, Hung-Yu, Wu, Huang-Pin, Chu, Chien-Ming, Huang, Chih-Yu, Liu, Ping-Chi, Liu, Yung-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914863/
https://www.ncbi.nlm.nih.gov/pubmed/33567713
http://dx.doi.org/10.3390/ijms22041702

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914863/
https://www.ncbi.nlm.nih.gov/pubmed/33567713
http://dx.doi.org/10.3390/ijms22041702

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