Metformin and Androgen Receptor-Axis-Targeted (ARAT) Agents Induce Two PARP-1-Dependent Cell Death Pathways in Androgen-Sensitive Human Prostate Cancer Cells

SIMPLE SUMMARY: In the present study, we sought to determine whether a commonly used oral drug to treat adult-onset diabetes, metformin, which has a longstanding clinical history and known safety and tolerability profile, can improve the anti-cancer effects of two well-established oral agents curren...

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Detalles Bibliográficos
Autores principales: Xie, Yi, Wang, Linbo, Khan, Mohammad A., Hamburger, Anne W., Guang, Wei, Passaniti, Antonino, Munir, Kashif, Ross, Douglas D., Dean, Michael, Hussain, Arif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914929/
https://www.ncbi.nlm.nih.gov/pubmed/33562646
http://dx.doi.org/10.3390/cancers13040633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914929/
https://www.ncbi.nlm.nih.gov/pubmed/33562646
http://dx.doi.org/10.3390/cancers13040633

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