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Novel Use of PLGA Microspheres to Create an Animal Model of Glaucoma with Progressive Neuroretinal Degeneration

Progressive degeneration of neuroretinal tissue with maintained elevated intraocular pressure (IOP) to simulate chronic glaucoma was produced by intracameral injections of poly (lactic-co-glycolic) acid (PLGA) microspheres (Ms) in rat eyes. The right eye of 39 rats received different sizes of PLGA-M...

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Detalles Bibliográficos
Autores principales: Garcia-Herranz, David, Rodrigo, Maria Jesus, Subias, Manuel, Martinez-Rincon, Teresa, Mendez-Martinez, Silvia, Bravo-Osuna, Irene, Bonet, Aina, Ruberte, Jesus, Garcia-Feijoo, Julian, Pablo, Luis, Garcia-Martin, Elena, Herrero-Vanrell, Rocío
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915113/
https://www.ncbi.nlm.nih.gov/pubmed/33567776
http://dx.doi.org/10.3390/pharmaceutics13020237