Cargando…
Novel Use of PLGA Microspheres to Create an Animal Model of Glaucoma with Progressive Neuroretinal Degeneration
Progressive degeneration of neuroretinal tissue with maintained elevated intraocular pressure (IOP) to simulate chronic glaucoma was produced by intracameral injections of poly (lactic-co-glycolic) acid (PLGA) microspheres (Ms) in rat eyes. The right eye of 39 rats received different sizes of PLGA-M...
Autores principales: | Garcia-Herranz, David, Rodrigo, Maria Jesus, Subias, Manuel, Martinez-Rincon, Teresa, Mendez-Martinez, Silvia, Bravo-Osuna, Irene, Bonet, Aina, Ruberte, Jesus, Garcia-Feijoo, Julian, Pablo, Luis, Garcia-Martin, Elena, Herrero-Vanrell, Rocío |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915113/ https://www.ncbi.nlm.nih.gov/pubmed/33567776 http://dx.doi.org/10.3390/pharmaceutics13020237 |
Ejemplares similares
-
Long-term corticosteroid-induced chronic glaucoma model produced by intracameral injection of dexamethasone-loaded PLGA microspheres
por: Rodrigo, MJ, et al.
Publicado: (2021) -
Mimicking chronic glaucoma over 6 months with a single intracameral injection of dexamethasone/fibronectin-loaded PLGA microspheres
por: Aragón-Navas, Alba, et al.
Publicado: (2022) -
Chronic Glaucoma Using Biodegradable Microspheres to Induce Intraocular Pressure Elevation. Six-Month Follow-Up
por: Rodrigo, Maria Jesus, et al.
Publicado: (2021) -
Influence of Sex on Neuroretinal Degeneration: Six-Month Follow-Up in Rats With Chronic Glaucoma
por: Rodrigo, Maria J., et al.
Publicado: (2021) -
Tunable degrees of neurodegeneration in rats based on microsphere-induced models of chronic glaucoma
por: Rodrigo, María Jesús, et al.
Publicado: (2022)