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AAV-Mediated CRISPRi and RNAi Based Gene Silencing in Mouse Hippocampal Neurons

Uncovering the physiological role of individual proteins that are part of the intricate process of cellular signaling is often a complex and challenging task. A straightforward strategy of studying a protein’s function is by manipulating the expression rate of its gene. In recent years, the Clustere...

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Detalles Bibliográficos
Autores principales: Deutsch, Matthias, Günther, Anne, Lerchundi, Rodrigo, Rose, Christine R., Balfanz, Sabine, Baumann, Arnd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915209/
https://www.ncbi.nlm.nih.gov/pubmed/33557342
http://dx.doi.org/10.3390/cells10020324