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Amino Acylguanidines as Bioinspired Catalysts for the Asymmetric Aldol Reaction

The binding and stabilizing effect of arginine residues in certain aldolases served as inspiring source for the development of a family of amino acylguanidine organocatalysts. Screening and optimization led to identify the threonine derivative as the most suitable catalyst for the asymmetric aldol a...

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Detalles Bibliográficos
Autor principal: Jimeno, Ciril
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915246/
https://www.ncbi.nlm.nih.gov/pubmed/33562560
http://dx.doi.org/10.3390/molecules26040826