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Amino Acylguanidines as Bioinspired Catalysts for the Asymmetric Aldol Reaction
The binding and stabilizing effect of arginine residues in certain aldolases served as inspiring source for the development of a family of amino acylguanidine organocatalysts. Screening and optimization led to identify the threonine derivative as the most suitable catalyst for the asymmetric aldol a...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915246/ https://www.ncbi.nlm.nih.gov/pubmed/33562560 http://dx.doi.org/10.3390/molecules26040826 |