Genetic Bias, Diversity Indices, Physiochemical Properties and CDR3 Motifs Divide Auto-Reactive from Allo-Reactive T-Cell Repertoires

The distinct properties of allo-reactive T-cell repertoires are not well understood. To investigate whether auto-reactive and allo-reactive T-cell repertoires encoded distinct properties, we used dextramer enumeration, enrichment, single-cell T-cell receptor (TCR) sequencing and multiparameter analy...

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Detalles Bibliográficos
Autores principales: Haigh, Oscar L., Grant, Emma J., Nguyen, Thi H. O., Kedzierska, Katherine, Field, Matt A., Miles, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915266/
https://www.ncbi.nlm.nih.gov/pubmed/33562731
http://dx.doi.org/10.3390/ijms22041625

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915266/
https://www.ncbi.nlm.nih.gov/pubmed/33562731
http://dx.doi.org/10.3390/ijms22041625

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