Cargando…

The Endothelium as a Target for Anti-Atherogenic Therapy: A Focus on the Epigenetic Enzymes EZH2 and SIRT1

Endothelial cell inflammatory activation and dysfunction are key events in the pathophysiology of atherosclerosis, and are associated with an elevated risk of cardiovascular events. Yet, therapies specifically targeting the endothelium and atherosclerosis are lacking. Here, we review how endothelial...

Descripción completa

Detalles Bibliográficos
Autores principales: Fledderus, Jolien, Vanchin, Byambasuren, Rots, Marianne G., Krenning, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915331/
https://www.ncbi.nlm.nih.gov/pubmed/33562658
http://dx.doi.org/10.3390/jpm11020103