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Selective Targeting of Cancer-Associated Fibroblasts by Engineered H-Ferritin Nanocages Loaded with Navitoclax

Cancer-associated fibroblasts (CAFs) are key actors in regulating cancer progression. They promote tumor growth, metastasis formation, and induce drug resistance. For these reasons, they are emerging as potential therapeutic targets. Here, with the aim of developing CAF-targeted drug delivery agents...

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Detalles Bibliográficos
Autores principales: Sitia, Leopoldo, Bonizzi, Arianna, Mazzucchelli, Serena, Negri, Sara, Sottani, Cristina, Grignani, Elena, Rizzuto, Maria Antonietta, Prosperi, Davide, Sorrentino, Luca, Morasso, Carlo, Allevi, Raffaele, Sevieri, Marta, Silva, Filippo, Truffi, Marta, Corsi, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915356/
https://www.ncbi.nlm.nih.gov/pubmed/33562504
http://dx.doi.org/10.3390/cells10020328