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Selective Targeting of Cancer-Associated Fibroblasts by Engineered H-Ferritin Nanocages Loaded with Navitoclax
Cancer-associated fibroblasts (CAFs) are key actors in regulating cancer progression. They promote tumor growth, metastasis formation, and induce drug resistance. For these reasons, they are emerging as potential therapeutic targets. Here, with the aim of developing CAF-targeted drug delivery agents...
Autores principales: | Sitia, Leopoldo, Bonizzi, Arianna, Mazzucchelli, Serena, Negri, Sara, Sottani, Cristina, Grignani, Elena, Rizzuto, Maria Antonietta, Prosperi, Davide, Sorrentino, Luca, Morasso, Carlo, Allevi, Raffaele, Sevieri, Marta, Silva, Filippo, Truffi, Marta, Corsi, Fabio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915356/ https://www.ncbi.nlm.nih.gov/pubmed/33562504 http://dx.doi.org/10.3390/cells10020328 |
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