IL-17A and TNF Modulate Normal Human Spinal Entheseal Bone and Soft Tissue Mesenchymal Stem Cell Osteogenesis, Adipogenesis, and Stromal Function

Objective: The spondylarthritides (SpA) are intimately linked to new bone formation and IL-17A and TNF pathways. We investigated spinal soft tissue and bone mesenchymal stem cell (MSC) responses to IL-17A and TNF, including their osteogenesis, adipogenesis, and stromal supportive function and abilit...

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Detalles Bibliográficos
Autores principales: Russell, Tobias, Watad, Abdulla, Bridgewood, Charlie, Rowe, Hannah, Khan, Almas, Rao, Abhay, Loughenbury, Peter, Millner, Peter, Dunsmuir, Robert, Cuthbert, Richard, Altaie, Ala, Jones, Elena, McGonagle, Dennis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915379/
https://www.ncbi.nlm.nih.gov/pubmed/33562025
http://dx.doi.org/10.3390/cells10020341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915379/
https://www.ncbi.nlm.nih.gov/pubmed/33562025
http://dx.doi.org/10.3390/cells10020341

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