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Increase in the risk of clopidogrel resistance and consequent TIMI flow impairment by DNA hypomethylation of CYP2C19 gene in STEMI patients undergoing primary percutaneous coronary intervention (PPCI)

Clopidogrel resistance is an important risk factor of ischemic event recurrence after optimal antiplatelet therapy. This study aims to investigate the role of CYP2C19 gene DNA methylation as one of the epigenetic factors for the risk of clopidogrel resistance in STEMI patients undergoing PPCI. ST‐se...

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Detalles Bibliográficos
Autores principales: Sukmawan, Renan, Hoetama, Erick, Suridanda Danny, Siska, Giantini, Astuti, Listiyaningsih, Erlin, Gilang Rejeki, Vidya, Aziz Alkatiri, Amir, Firdaus, Isman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915409/
https://www.ncbi.nlm.nih.gov/pubmed/33641235
http://dx.doi.org/10.1002/prp2.738