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EphA2 and EGFR: Friends in Life, Partners in Crime. Can EphA2 Be a Predictive Biomarker of Response to Anti-EGFR Agents?

SIMPLE SUMMARY: The Ephrin receptors and their ligands play important roles in organ formation and tissue repair, by orchestrating complex programs of cell adhesion and repulsion, however, this same system plays a role in cancer development In fact, EphA2 levels are higher in tumors vs normal tissue...

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Detalles Bibliográficos
Autores principales: Cioce, Mario, Fazio, Vito Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915460/
https://www.ncbi.nlm.nih.gov/pubmed/33572284
http://dx.doi.org/10.3390/cancers13040700