Deep Impact of Random Amplification and Library Construction Methods on Viral Metagenomics Results

Clinical metagenomics is a broad-range agnostic detection method of pathogens, including novel microorganisms. A major limit is the low pathogen load compared to the high background of host nucleic acids. To overcome this issue, several solutions exist, such as applying a very high depth of sequenci...

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Detalles Bibliográficos
Autores principales: Regnault, Béatrice, Bigot, Thomas, Ma, Laurence, Pérot, Philippe, Temmam, Sarah, Eloit, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915491/
https://www.ncbi.nlm.nih.gov/pubmed/33562285
http://dx.doi.org/10.3390/v13020253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915491/
https://www.ncbi.nlm.nih.gov/pubmed/33562285
http://dx.doi.org/10.3390/v13020253

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